Ube2j2 | ubiquitin-conjugating enzyme E2J 2

GeneMGI:2153608Synonyms: Ubc6, 2400008G19Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Adipose tissue Growth/size/body region Limbs/digits/tail Liver/biliary system Hematopoietic system Behavior/neurological Skeleton

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:24Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased bone mineral density	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	2.07x10^-7
hyperactivity	2 supporting datasets	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	7.84x10^-7
abnormal epididymis morphology	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
decreased erythrocyte cell number	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	6.51x10^-6
small epididymis	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	4.66x10^-10
increased mean corpuscular hemoglobin	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	4.39x10^-12
increased total body fat amount	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Early adult	8.24x10^-6
abnormal spatial working memory	1 supporting dataset	Ube2j2^{em1(IMPC)Rbrc}	homozygote	Late adult	1.77x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ube2j2.

Associated images

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Histopathology

There is no histopathology data found for Ube2j2.

IMPC related publications

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External links

No external links available for Ube2j2.

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*Ube2j2^{em1(IMPC)Rbrc}*	Exon Deletion	‌	mouse
*Ube2j2^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Ube2j2^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Ube2j2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ube2j2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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