Elmo1 | engulfment and cell motility 1

GeneMGI:2153044Synonyms: 6330578D22Rik, CED-12, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength2 supporting datasetsElmo1tm1a(EUCOMM)WtsihomozygoteEarly adult2.59x10-7 
decreased fasting circulating glucose level1 supporting datasetElmo1tm1a(EUCOMM)WtsihomozygoteEarly adult1.4x10-5 
increased leukocyte cell number1 supporting datasetElmo1tm1a(EUCOMM)WtsihomozygoteEarly adult2.04x10-37 
increased mean corpuscular hemoglobin1 supporting datasetElmo1tm1a(EUCOMM)WtsihomozygoteEarly adult1.45x10-5 
increased lean body mass1 supporting datasetElmo1tm1a(EUCOMM)WtsihomozygoteEarly adult9.55x10-5 
increased red blood cell distribution width1 supporting datasetElmo1tm1a(EUCOMM)WtsihomozygoteEarly adult4.01x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Elmo1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)es cell
mouse

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