Usp3 | ubiquitin specific peptidase 3

GeneMGI:2152450

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

18 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Allele:



preweaning lethality, incomplete penetrance	1 supporting dataset	Usp3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Usp3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp3.

Associated images

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Histopathology

There is no histopathology data found for Usp3.

IMPC related publications

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External links

No external links available for Usp3.

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*Usp3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Usp3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Usp3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Usp3^{tm42256(pL1L2_GT2_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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