Mreg | melanoregulin

GeneMGI:2151839Synonyms: LOC381269, Wdt2, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Growth/size/body region Nervous system Hearing/vestibular/ear

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal lymph node morphology	1 supporting dataset	Mreg^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	N/A ^*
abnormal auditory brainstem response	1 supporting dataset	Mreg^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.07x10^-6
decreased body length	1 supporting dataset	Mreg^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.45x10^-6
decreased prepulse inhibition	1 supporting dataset	Mreg^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	5.59x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mreg.

Associated images

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Histopathology

There is no histopathology data found for Mreg.

IMPC related publications

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External links

No external links available for Mreg.

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*Mreg^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Mreg^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mreg^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mreg^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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