Stim2 | stromal interaction molecule 2

GeneMGI:2151156

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Nervous system Vision/eye Hearing/vestibular/ear Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	1 supporting dataset	Stim2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	4.69x10^-5
hyperactivity	5 supporting datasets	Stim2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.26x10^-5
decreased prepulse inhibition	1 supporting dataset	Stim2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.56x10^-5
abnormal auditory brainstem response	1 supporting dataset	Stim2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.04x10^-7
increased startle reflex	1 supporting dataset	Stim2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9.85x10^-7
cataract	1 supporting dataset	Stim2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.83x10^-6
impaired pupillary reflex	1 supporting dataset	Stim2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	5.43x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stim2.

Associated images

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Histopathology

There is no histopathology data found for Stim2.

IMPC related publications

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External links

No external links available for Stim2.

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*Stim2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Stim2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Stim2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Stim2^{tm44839(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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