Baz2a | bromodomain adjacent to zinc finger domain, 2A

GeneMGI:2151152Synonyms: C030005G16Rik, Tip5, +1 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Hematopoietic system Renal/urinary system

12 No significant impact

5 Not tested

Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating sodium level1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adult3.29x10-5 
small testis1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adultN/A * 
small epididymis1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adultN/A * 
increased blood urea nitrogen level1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adult1.24x10-9 
increased circulating alkaline phosphatase level1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adult5.21x10-5 
small kidney1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adultN/A * 
decreased fasting circulating glucose level1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adult3.05x10-5 
abnormal skin morphology1 supporting datasetBaz2aem1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Baz2aem1(IMPC)TcpExon Deletionmouse
Baz2atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Baz2atm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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