Foxn4 | forkhead box N4

Physiological systems

23 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Immune system Integument Adipose tissue Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Craniofacial

12 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased lean body mass	2 supporting datasets	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.15x10^-7
decreased prepulse inhibition	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	8.83x10^-6
abnormal cranium morphology	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	5.67x10^-6
increased total body fat amount	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	6.62x10^-5
abnormal skin morphology	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal tooth color	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.12x10^-5
increased freezing behavior	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	6.77x10^-8
no spontaneous movement	1 supporting dataset	Foxn4^{em1(IMPC)Ccpcz}	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Foxn4.

Associated images

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Histopathology

There is no histopathology data found for Foxn4.

IMPC related publications

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External links

No external links available for Foxn4.

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*Foxn4^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse
*Foxn4^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Foxn4^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Foxn4^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell
*Foxn4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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