Cnnm2 | cyclin M2

GeneMGI:2151054Synonyms: Acdp2

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Nervous system Vision/eye Skeleton Cardiovascular system Mortality/aging Craniofacial

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

3Associated diseases

Expression examined in:73Adult tissues

84Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal head shape	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
edema	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
hemorrhage	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
exencephaly	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
hemorrhage	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	heterozygote	E15.5	N/A ^*
increased bone mineral density	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	6.22x10^-5
embryonic growth retardation	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
microcephaly	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
spina bifida	1 supporting dataset	Cnnm2^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cnnm2.

Associated images

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Histopathology

There is no histopathology data found for Cnnm2.

IMPC related publications

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External links

No external links available for Cnnm2.

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*Cnnm2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Cnnm2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Cnnm2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cnnm2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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