Grin3b | glutamate receptor, ionotropic, NMDA3B

GeneMGI:2150393Synonyms: NR3B

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating potassium level	1 supporting dataset	Grin3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.16x10^-5
abnormal gait	1 supporting dataset	Grin3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.29x10^-10
increased circulating bilirubin level	1 supporting dataset	Grin3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.98x10^-8
decreased circulating triglyceride level	1 supporting dataset	Grin3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.78x10^-7
increased red blood cell distribution width	1 supporting dataset	Grin3b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.34x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Grin3b.

Associated images

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Histopathology

There is no histopathology data found for Grin3b.

IMPC related publications

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External links

No external links available for Grin3b.

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*Grin3b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Grin3b^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Grin3b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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