Srd5a2 | steroid 5 alpha-reductase 2

GeneMGI:2150380Synonyms: 5ART2

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Vision/eye Hematopoietic system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal testis morphology	1 supporting dataset	Srd5a2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Srd5a2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Srd5a2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Srd5a2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Srd5a2^em1(IMPC)Mbp	homozygote	Early adult	5.3x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Srd5a2.

Associated images

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Histopathology

There is no histopathology data found for Srd5a2.

IMPC related publications

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External links

No external links available for Srd5a2.

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*Srd5a2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Srd5a2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Srd5a2^{tm374832(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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