Ubqln4 | ubiquilin 4

GeneMGI:2150152Synonyms: UBIN

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Liver/biliary system Hematopoietic system Behavior/neurological

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	4 supporting datasets	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	9.89x10^-8
decreased brain size	2 supporting datasets	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased locomotor activity	2 supporting datasets	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	5.15x10^-5
abnormal spleen morphology	1 supporting dataset	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal brain morphology	2 supporting datasets	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small liver	1 supporting dataset	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enhanced cued conditioning behavior	1 supporting dataset	Ubqln4^em1(IMPC)Mbp	homozygote	Early adult	4.81x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ubqln4.

Associated images

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Histopathology

There is no histopathology data found for Ubqln4.

IMPC related publications

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External links

No external links available for Ubqln4.

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*Ubqln4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Ubqln4^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ubqln4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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