Slc4a10 | solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

GeneMGI:2150150Synonyms: NCBE

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral content	1 supporting dataset	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.33x10^-5
abnormal auditory brainstem response	3 supporting datasets	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.63x10^-7
hyperactivity	1 supporting dataset	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.43x10^-6
increased hemoglobin content	1 supporting dataset	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.98x10^-7
abnormal gait	1 supporting dataset	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.91x10^-5
increased startle reflex	1 supporting dataset	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.74x10^-7
small spleen	1 supporting dataset	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Slc4a10^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.82x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc4a10.

Associated images

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Histopathology

There is no histopathology data found for Slc4a10.

IMPC related publications

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External links

No external links available for Slc4a10.

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*Slc4a10^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc4a10^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc4a10^{tm34451(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Slc4a10^{tm356009(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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