Spred2 | sprouty-related EVH1 domain containing 2
Physiological systems
21 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Integument Growth/size/body region Digestive/alimentary Nervous system Vision/eye Liver/biliary system Hematopoietic system Renal/urinary system
11 No significant impact
3 Not tested
Data collections
Gene metrics:14Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased brain size | 2 supporting datasets | Spred2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased mean corpuscular volume | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | 3.43x10-5 | ||
| abnormal liver morphology | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | 1.36x10-5 | ||
| enlarged stomach | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | 5.65x10-6 | ||
| increased circulating bilirubin level | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | 9.91x10-6 | ||
| abnormal skin morphology | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged kidney | 1 supporting dataset | Spred2em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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External links
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| Spred2em1(IMPC)Mbp | Exon Deletion | | mouse |