Pawr | PRKC, apoptosis, WT1, regulator

GeneMGI:2149961Synonyms: Par4, 2310001G03Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity5 supporting datasetsPawrtm1b(EUCOMM)WtsiheterozygoteEarly adult3.94x10-5 
decreased circulating creatinine level1 supporting datasetPawrtm1b(EUCOMM)WtsiheterozygoteEarly adult3.52x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetPawrtm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pawrtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Pawrtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Pawrtm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pawrtm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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