Hsd17b11 | hydroxysteroid (17-beta) dehydrogenase 11
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system Renal/urinary system
13 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| hyperactivity | 5 supporting datasets | Hsd17b11tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.86x10-6 | ||
| increased heart weight | 1 supporting dataset | Hsd17b11tm1.1(KOMP)Vlcg | homozygote | Early adult | 1.66x10-7 | ||
| decreased urine microalbumin level | 1 supporting dataset | Hsd17b11tm1.1(KOMP)Vlcg | homozygote | Early adult | 8.49x10-5 | ||
| decreased urine creatinine level | 1 supporting dataset | Hsd17b11tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.05x10-7 |
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External links
No external links available for Hsd17b11.
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| Hsd17b11tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Hsd17b11tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Hsd17b11tm221053(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |