Slc13a3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

GeneMGI:2149635Synonyms: NaDC3, NaDC-3, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Respiratory system Hematopoietic system

17 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased circulating creatinine level1 supporting datasetSlc13a3tm1b(KOMP)WtsihomozygoteEarly adult1.58x10-13 
increased neutrophil cell number1 supporting datasetSlc13a3tm1b(KOMP)WtsihomozygoteEarly adult1.18x10-6 
increased monocyte cell number1 supporting datasetSlc13a3tm1b(KOMP)WtsihomozygoteEarly adult1.52x10-5 
increased pulmonary ventilation1 supporting datasetSlc13a3tm1b(KOMP)WtsihomozygoteEarly adult4.25x10-5 
decreased lymphocyte cell number1 supporting datasetSlc13a3tm1b(KOMP)WtsihomozygoteEarly adult2.09x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc13a3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc13a3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Slc13a3tm355928(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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