Cygb | cytoglobin

GeneMGI:2149481Synonyms: 3110001K20Rik, Staap

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Adipose tissue Growth/size/body region Skeleton Cardiovascular system Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total body fat amount	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.19x10^-5
abnormal heart morphology	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating cholesterol level	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.36x10^-5
increased heart weight	2 supporting datasets	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.74x10^-9
abnormal testis morphology	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.22x10^-5
enlarged heart	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.19x10^-5
small testis	1 supporting dataset	Cygb^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cygb.

Associated images

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Histopathology

There is no histopathology data found for Cygb.

IMPC related publications

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External links

No external links available for Cygb.

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*Cygb^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cygb^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cygb^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Cygb^{tm40214(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cygb^{tm40214(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cygb^{tm40214(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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