Dock2 | dedicator of cyto-kinesis 2

GeneMGI:2149010Synonyms: CED-5, MBC, +1 more

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Skeleton

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased spleen weight	1 supporting dataset	Dock2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.37x10^-6
decreased bone mineral density	1 supporting dataset	Dock2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.04x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dock2.

Associated images

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Histopathology

There is no histopathology data found for Dock2.

IMPC related publications

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External links

No external links available for Dock2.

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*Dock2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dock2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dock2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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