Ehmt2 | euchromatic histone lysine N-methyltransferase 2
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Embryo Growth/size/body region Behavior/neurological Mortality/aging
16 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal locomotor behavior | 1 supporting dataset | Ehmt2tm1.1(KOMP)Mbp | heterozygote | Early adult | 6.99x10-6 | ||
| decreased exploration in new environment | 1 supporting dataset | Ehmt2tm1.1(KOMP)Mbp | heterozygote | Early adult | 5.64x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Ehmt2tm1.1(KOMP)Mbp | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ehmt2tm1.1(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| hyperactivity | 1 supporting dataset | Ehmt2tm1.1(KOMP)Mbp | heterozygote | Early adult | 7.09x10-6 | ||
| embryonic growth retardation | 1 supporting dataset | Ehmt2tm1.1(KOMP)Mbp | homozygote | E9.5 | N/A * |
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External links
No external links available for Ehmt2.
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| Ehmt2tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Ehmt2tm1.1(KOMP)Mbp | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Ehmt2tm448485(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |