Sec16b | SEC16 homolog B, endoplasmic reticulum export factor

GeneMGI:2148802Synonyms: Rgpr-p117, Rgpr, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

15 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased circulating LDL cholesterol level1 supporting datasetSec16btm1a(KOMP)WtsihomozygoteEarly adult4.71x10-7 
decreased circulating HDL cholesterol level1 supporting datasetSec16btm1a(KOMP)WtsihomozygoteEarly adult4.04x10-14 
decreased circulating cholesterol level1 supporting datasetSec16btm1a(KOMP)WtsihomozygoteEarly adult2.62x10-13 
increased leukocyte cell number1 supporting datasetSec16btm1a(KOMP)WtsihomozygoteEarly adult1.67x10-5 
abnormal tail movements1 supporting datasetSec16btm1a(KOMP)WtsihomozygoteEarly adult1.17x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sec16btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Sec16btm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Sec16btm41606(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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