Sec16b | SEC16 homolog B, endoplasmic reticulum export factor
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| decreased circulating LDL cholesterol level | 1 supporting dataset | Sec16btm1a(KOMP)Wtsi | homozygote | Early adult | 4.71x10-7 | ||
| decreased circulating HDL cholesterol level | 1 supporting dataset | Sec16btm1a(KOMP)Wtsi | homozygote | Early adult | 4.04x10-14 | ||
| decreased circulating cholesterol level | 1 supporting dataset | Sec16btm1a(KOMP)Wtsi | homozygote | Early adult | 2.62x10-13 | ||
| increased leukocyte cell number | 1 supporting dataset | Sec16btm1a(KOMP)Wtsi | homozygote | Early adult | 1.67x10-5 | ||
| abnormal tail movements | 1 supporting dataset | Sec16btm1a(KOMP)Wtsi | homozygote | Early adult | 1.17x10-5 |
| | | | | | | | | | |
External links
No external links available for Sec16b.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Sec16btm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Sec16btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Sec16btm41606(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |