Kiss1r | KISS1 receptor

GeneMGI:2148793Synonyms: Gpr54

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Renal/urinary system

10 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:28Significant phenotypes

5Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	4 supporting datasets	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.56x10^-6
increased thymus weight	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	8.78x10^-5
abnormal kidney morphology	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
absent ovary	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased bone mineral content	2 supporting datasets	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.89x10^-25
small kidney	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
absent testes	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
absent epididymis	1 supporting dataset	Kiss1r^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kiss1r.

Associated images

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Histopathology

There is no histopathology data found for Kiss1r.

IMPC related publications

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External links

No external links available for Kiss1r.

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*Kiss1r^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Kiss1r^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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