Cldn16 | claudin 16

GeneMGI:2148742Synonyms: paracellin-1, PCLN1, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating calcium level	1 supporting dataset	Cldn16^{tm1a(KOMP)Wtsi}	homozygote	Early adult	9.88x10^-12
decreased bone mineral content	1 supporting dataset	Cldn16^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.03x10^-5
increased circulating amylase level	1 supporting dataset	Cldn16^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.25x10^-6
increased circulating creatinine level	1 supporting dataset	Cldn16^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.41x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Cldn16.

Associated images

Loading...

Histopathology

There is no histopathology data found for Cldn16.

IMPC related publications

Loading...

External links

No external links available for Cldn16.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Cldn16^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Cldn16^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cldn16^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell
*Cldn16^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Cldn16^{tm46517(L1L2_hubi_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes