Ces1d | carboxylesterase 1D

GeneMGI:2148202Synonyms: TGH, Ces3

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Renal/urinary system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal kidney morphology	1 supporting dataset	Ces1d^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Ces1d^em1(IMPC)Mbp	homozygote	Early adult	2.37x10^-33
increased circulating aspartate transaminase level	1 supporting dataset	Ces1d^em1(IMPC)Mbp	homozygote	Early adult	1.43x10^-5
polycystic kidney	1 supporting dataset	Ces1d^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ces1d.

Associated images

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Histopathology

There is no histopathology data found for Ces1d.

IMPC related publications

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External links

No external links available for Ces1d.

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*Ces1d^em1(IMPC)Mbp*	Indel	‌	mouse
*Ces1d^{tm42913(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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