Fermt3 | fermitin family member 3

GeneMGI:2147790Synonyms: Kindlin-3, C79673

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging Cardiovascular system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Fermt3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
edema	1 supporting dataset	Fermt3^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*
hemorrhage	1 supporting dataset	Fermt3^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fermt3.

Associated images

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Histopathology

There is no histopathology data found for Fermt3.

IMPC related publications

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External links

No external links available for Fermt3.

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*Fermt3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fermt3^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fermt3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Fermt3^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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