Slc6a7 | solute carrier family 6 (neurotransmitter transporter, L-proline), member 7

GeneMGI:2147363Synonyms: Prot

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetSlc6a7em1(IMPC)JhomozygoteEarly adultN/A * 
increased exploration in new environment1 supporting datasetSlc6a7em1(IMPC)JhomozygoteEarly adult4.57x10-7 
increased grip strength1 supporting datasetSlc6a7em1(IMPC)JhomozygoteEarly adult4.36x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Slc6a7em1(IMPC)JExon Deletionmouse
Slc6a7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slc6a7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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