Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

GeneMGI:2147274Synonyms: Centd3, DRAG1, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetArap3em1(IMPC)JhomozygoteEarly adult3.94x10-5 
impaired pupillary reflex1 supporting datasetArap3em1(IMPC)JhomozygoteEarly adult1.28x10-8 
abnormal vibrissa morphology1 supporting datasetArap3em1(IMPC)JhomozygoteLate adult7.18x10-9 
hyperactivity3 supporting datasetsArap3em1(IMPC)JhomozygoteEarly adult1.11x10-5 
decreased thigmotaxis2 supporting datasetsArap3em1(IMPC)JhomozygoteEarly adult3.33x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arap3em1(IMPC)JExon Deletionmouse
Arap3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Arap3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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