Pkdcc | protein kinase domain containing, cytoplasmic

GeneMGI:2147077Synonyms: Adtk1, ESTM17, +2 more

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Nervous system Liver/biliary system Behavior/neurological Mortality/aging Craniofacial Cardiovascular system Renal/urinary system

12 No significant impact

2 Not tested

Gene metrics:17Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

edema1 supporting datasetPkdccem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal liver morphology1 supporting datasetPkdccem1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetPkdccem1(IMPC)MbphomozygoteE9.5N/A * 
abnormal facial morphology1 supporting datasetPkdccem1(IMPC)MbphomozygoteE18.5N/A * 
abnormal placenta vasculature1 supporting datasetPkdccem1(IMPC)MbpheterozygoteE15.5N/A * 
abnormal facial morphology1 supporting datasetPkdccem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal placenta morphology1 supporting datasetPkdccem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal hindbrain development1 supporting datasetPkdccem1(IMPC)MbphomozygoteE9.5N/A * 
abnormal craniofacial morphology1 supporting datasetPkdccem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal placenta morphology1 supporting datasetPkdccem1(IMPC)MbpheterozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pkdccem1(IMPC)MbpExon Deletionmouse
Pkdcctm92111(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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