Arhgap28 | Rho GTPase activating protein 28

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Embryo Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system Renal/urinary system

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta vasculature	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
hemorrhage	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal placenta vasculature	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
small kidney	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
no spontaneous movement	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
no spontaneous movement	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Arhgap28^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Arhgap28^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Arhgap28.

Associated images

Loading...

Histopathology

There is no histopathology data found for Arhgap28.

IMPC related publications

Loading...

External links

No external links available for Arhgap28.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Arhgap28^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Arhgap28^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Arhgap28^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Arhgap28^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Arhgap28^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes