AU021092 | expressed sequence AU021092

GeneMGI:2146559

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system Renal/urinary system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



enlarged heart	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating glucose level	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.05x10^-5
hyperactivity	2 supporting datasets	AU021092^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.76x10^-5
increased heart weight	2 supporting datasets	AU021092^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.81x10^-15
abnormal kidney morphology	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal urinary bladder morphology	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating calcium level	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.69x10^-5
abnormal heart morphology	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	AU021092^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for AU021092.

Associated images

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Histopathology

There is no histopathology data found for AU021092.

IMPC related publications

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External links

No external links available for AU021092.

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*AU021092^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*AU021092^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*AU021092^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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