Osbpl11 | oxysterol binding protein-like 11

GeneMGI:2146553Synonyms: ORP-11

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount1 supporting datasetOsbpl11tm1b(EUCOMM)HmguheterozygoteEarly adult2.66x10-6 
decreased circulating triglyceride level1 supporting datasetOsbpl11tm1b(EUCOMM)HmguheterozygoteEarly adult1.66x10-5 
preweaning lethality, complete penetrance1 supporting datasetOsbpl11tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
improved glucose tolerance1 supporting datasetOsbpl11tm1b(EUCOMM)HmguheterozygoteEarly adult6.21x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Osbpl11tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Osbpl11tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Osbpl11tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter