Rimoc1 | RAB7A interacting MON1-CCZ1 complex subunit 1

GeneMGI:2146232Synonyms: AW549877

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Skeleton Cardiovascular system

14 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

abnormal retina inner nuclear layer morphology2 supporting datasetsRimoc1tm1b(EUCOMM)WtsihomozygoteEarly adult1.02x10-6 
increased body temperature1 supporting datasetRimoc1tm1b(EUCOMM)WtsihomozygoteEarly adult2.22x10-5 
decreased total retina thickness2 supporting datasetsRimoc1tm1b(EUCOMM)WtsihomozygoteEarly adult4.06x10-13 
abnormal retina blood vessel morphology1 supporting datasetRimoc1tm1b(EUCOMM)WtsihomozygoteEarly adult1.59x10-6 
increased bone mineral density1 supporting datasetRimoc1tm1b(EUCOMM)WtsihomozygoteEarly adult1.98x10-6 
abnormal retina outer nuclear layer morphology2 supporting datasetsRimoc1tm1b(EUCOMM)WtsihomozygoteEarly adult2.04x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rimoc1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rimoc1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Rimoc1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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