Washc5 | WASH complex subunit 5

GeneMGI:2146110Synonyms: E430025E21Rik, strumpellin

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetWashc5tm1a(EUCOMM)HmguhomozygoteEarly adultN/A * 
thrombocytopenia1 supporting datasetWashc5tm1a(EUCOMM)HmguheterozygoteEarly adult4.6x10-5 
increased mean corpuscular volume1 supporting datasetWashc5tm1a(EUCOMM)HmguheterozygoteEarly adult1.55x10-6 
decreased circulating glucose level1 supporting datasetWashc5tm1a(EUCOMM)HmguheterozygoteEarly adult1.95x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Washc5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Washc5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Washc5tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Washc5tm84190(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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