Fam83h | family with sequence similarity 83, member H

Physiological systems

24 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging Renal/urinary system

13 No significant impact

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:23Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



abnormal spleen morphology	2 supporting datasets	Fam83h^{em2(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal coat/ hair morphology	3 supporting datasets	Fam83h^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.72x10^-6
abnormal behavior	1 supporting dataset	Fam83h^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.25x10^-5
abnormal coat appearance	3 supporting datasets	Fam83h^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.32x10^-24
small testis	1 supporting dataset	Fam83h^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased locomotor activity	4 supporting datasets	Fam83h^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.27x10^-5
decreased grip strength	1 supporting dataset	Fam83h^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.17x10^-8
enlarged testis	1 supporting dataset	Fam83h^{em2(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	Fam83h^{em1(IMPC)Ccpcz}	homozygote	Early adult	1x10^-11
increased freezing behavior	2 supporting datasets	Fam83h^{em2(IMPC)Ccpcz}	heterozygote	Early adult	2.32x10^-19

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam83h.

Associated images

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Histopathology

There is no histopathology data found for Fam83h.

IMPC related publications

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External links

No external links available for Fam83h.

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*Fam83h^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Fam83h^{em2(IMPC)Ccpcz}*	Whole-gene deletion	‌	mouse
*Fam83h^{tm237040(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector

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