Cog5 | component of oligomeric golgi complex 5

GeneMGI:2145130Synonyms: GOLTC1, 5430405C01Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal heart morphology2 supporting datasetsCog5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsCog5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsCog5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal digit morphology1 supporting datasetCog5em1(IMPC)CcpczheterozygoteEarly adult8.91x10-14 
embryonic lethality prior to organogenesis1 supporting datasetCog5em1(IMPC)CcpczhomozygoteE9.5N/A * 
enlarged spleen2 supporting datasetsCog5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
decreased freezing behavior1 supporting datasetCog5em1(IMPC)CcpczheterozygoteEarly adult1.12x10-7 
embryonic lethality prior to tooth bud stage1 supporting datasetCog5em1(IMPC)CcpczhomozygoteE12.5N/A * 
enlarged heart2 supporting datasetsCog5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetCog5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cog5em1(IMPC)CcpczExon Deletionmouse

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