Pld4 | phospholipase D family member 4
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system
14 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged spleen | 2 supporting datasets | Pld4em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased spleen weight | 1 supporting dataset | Pld4em1(IMPC)Mbp | homozygote | Early adult | 2.29x10-6 | ||
| increased leukocyte cell number | 1 supporting dataset | Pld4em1(IMPC)Mbp | homozygote | Early adult | 7.95x10-5 | ||
| abnormal spleen morphology | 2 supporting datasets | Pld4em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased monocyte cell number | 1 supporting dataset | Pld4em1(IMPC)Mbp | homozygote | Early adult | 4.63x10-10 | ||
| eye hemorrhage | 1 supporting dataset | Pld4em1(IMPC)Mbp | homozygote | Early adult | 2.28x10-5 | ||
| cornea opacity | 1 supporting dataset | Pld4em1(IMPC)Mbp | homozygote | Early adult | 3.54x10-12 | ||
| decreased circulating calcium level | 1 supporting dataset | Pld4em1(IMPC)Mbp | homozygote | Early adult | 6.84x10-7 | ||
| increased lymphocyte cell number | 1 supporting dataset | Pld4em1(IMPC)Mbp | homozygote | Early adult | 9.4x10-5 |
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External links
No external links available for Pld4.
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| Pld4em1(IMPC)Mbp | Exon Deletion | | mouse |
| Pld4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |