Ankmy2 | ankyrin repeat and MYND domain containing 2

GeneMGI:2144755

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Nervous system Mortality/aging Cardiovascular system Craniofacial

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal hindbrain development	1 supporting dataset	Ankmy2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Ankmy2^em1(IMPC)Bay	heterozygote	E12.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Ankmy2^em1(IMPC)Bay	heterozygote	E12.5	N/A ^*
abnormal midbrain development	1 supporting dataset	Ankmy2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Ankmy2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal embryo turning	1 supporting dataset	Ankmy2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Ankmy2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal neural tube closure	1 supporting dataset	Ankmy2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Ankmy2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal forebrain development	1 supporting dataset	Ankmy2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ankmy2.

Associated images

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Histopathology

There is no histopathology data found for Ankmy2.

IMPC related publications

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External links

No external links available for Ankmy2.

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*Ankmy2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Ankmy2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ankmy2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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