Smg6 | SMG6 nonsense mediated mRNA decay factor
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Integument Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging
16 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged spleen | 1 supporting dataset | Smg6em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Smg6em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| scaly skin | 1 supporting dataset | Smg6em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Smg6em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 2 supporting datasets | Smg6em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Smg6em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal startle reflex | 1 supporting dataset | Smg6em1(IMPC)Mbp | heterozygote | Middle aged adult | 1.94x10-5 |
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External links
No external links available for Smg6.
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| Smg6em1(IMPC)Mbp | Exon Deletion | | mouse |
| Smg6tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Smg6tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |