Vezt | vezatin, adherens junctions transmembrane protein

GeneMGI:2143698

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased mean corpuscular volume	1 supporting dataset	Vezt^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.05x10^-6
decreased circulating glucose level	1 supporting dataset	Vezt^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.7x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Vezt^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased locomotor activity	4 supporting datasets	Vezt^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.07x10^-6
decreased vertical activity	1 supporting dataset	Vezt^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.77x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Vezt^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal coat appearance	1 supporting dataset	Vezt^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.17x10^-5
increased urine microalbumin level	1 supporting dataset	Vezt^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.94x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vezt.

Associated images

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Histopathology

There is no histopathology data found for Vezt.

IMPC related publications

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External links

No external links available for Vezt.

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*Vezt^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Vezt^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Vezt^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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