Chchd10 | coiled-coil-helix-coiled-coil-helix domain containing 10

GeneMGI:2143558Synonyms: 1620401E04Rik, Ndg2

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Behavior/neurological

16 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength2 supporting datasetsChchd10em1(IMPC)HhomozygoteEarly adult4.12x10-7 
small testis1 supporting datasetChchd10em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating creatinine level1 supporting datasetChchd10em1(IMPC)HhomozygoteEarly adult2.79x10-38 
increased blood urea nitrogen level1 supporting datasetChchd10em1(IMPC)HhomozygoteEarly adult5.7x10-13 
abnormal testis morphology1 supporting datasetChchd10em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating phosphate level1 supporting datasetChchd10em1(IMPC)MbphomozygoteEarly adult2.71x10-5 
increased circulating potassium level1 supporting datasetChchd10em1(IMPC)HhomozygoteEarly adult5.01x10-12 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Chchd10em1(IMPC)HExon Deletionmouse
Chchd10em1(IMPC)MbpExon Deletionmouse
Chchd10em2(IMPC)HExon Deletionmouse
Chchd10tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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