Upb1 | ureidopropionase, beta

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount1 supporting datasetUpb1tm1a(EUCOMM)WtsihomozygoteEarly adult5.75x10-6 
decreased lean body mass1 supporting datasetUpb1tm1a(EUCOMM)WtsihomozygoteEarly adult6.38x10-7 
decreased body length1 supporting datasetUpb1tm1a(EUCOMM)WtsihomozygoteEarly adult2.62x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Upb1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse

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