Bbs4 | Bardet-Biedl syndrome 4
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
15 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
42Embryo tissues
| decreased exploration in new environment | 1 supporting dataset | Bbs4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.35x10-9 | ||
| increased startle reflex | 1 supporting dataset | Bbs4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.75x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Bbs4tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased thigmotaxis | 2 supporting datasets | Bbs4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.45x10-8 | ||
| hyperactivity | 1 supporting dataset | Bbs4tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.01x10-5 |
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External links
No external links available for Bbs4.
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| Bbs4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Bbs4tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Bbs4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |