Il20rb | interleukin 20 receptor beta

GeneMGI:2143266Synonyms: Fndc6, LOC213208, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Nervous system Vision/eye

17 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal brain morphology1 supporting datasetIl20rbtm1b(KOMP)WtsihomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetIl20rbem2(IMPC)MbphomozygoteEarly adult2.87x10-5 
abnormal eye morphology2 supporting datasetsIl20rbem2(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetIl20rbtm1b(KOMP)WtsihomozygoteEarly adult4.21x10-6 
abnormal epididymis morphology1 supporting datasetIl20rbem2(IMPC)MbphomozygoteEarly adultN/A * 
enlarged epididymis1 supporting datasetIl20rbtm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
enlarged epididymis1 supporting datasetIl20rbem2(IMPC)MbphomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetIl20rbem2(IMPC)MbphomozygoteEarly adult5.13x10-5 
hydrocephaly1 supporting datasetIl20rbtm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il20rbem2(IMPC)MbpExon Deletionmouse
Il20rbtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Il20rbtm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Il20rbtm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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