Nkapd1 | NKAP domain containing 1
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Integument Embryo Nervous system Behavior/neurological Mortality/aging Cardiovascular system Renal/urinary system
14 No significant impact
3 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
embryonic lethality prior to organogenesis | 1 supporting dataset | Nkapd1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
abnormal kidney morphology | 1 supporting dataset | Nkapd1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Nkapd1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
decreased prepulse inhibition | 1 supporting dataset | Nkapd1em1(IMPC)Mbp | heterozygote | Early adult | 3.23x10-7 | ||
abnormal vitelline vasculature morphology | 1 supporting dataset | Nkapd1em1(IMPC)Mbp | heterozygote | E9.5 | N/A * | ||
abnormal skin morphology | 2 supporting datasets | Nkapd1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
increased freezing behavior | 1 supporting dataset | Nkapd1em1(IMPC)Mbp | heterozygote | Early adult | 7.16x10-9 | ||
abnormal visceral yolk sac morphology | 1 supporting dataset | Nkapd1em1(IMPC)Mbp | heterozygote | E9.5 | N/A * | ||
small kidney | 1 supporting dataset | Nkapd1em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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External links
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Nkapd1em1(IMPC)Mbp | Exon Deletion | | mouse |
Nkapd1tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |