Nkapd1 | NKAP domain containing 1

GeneMGI:2143205Synonyms: AU019823, LOC270156, +1 more

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Integument Embryo Nervous system Behavior/neurological Mortality/aging Cardiovascular system Renal/urinary system

14 No significant impact

3 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetNkapd1em1(IMPC)MbphomozygoteE9.5N/A * 
abnormal kidney morphology1 supporting datasetNkapd1em1(IMPC)MbpheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsNkapd1em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetNkapd1em1(IMPC)MbpheterozygoteEarly adult3.23x10-7 
abnormal vitelline vasculature morphology1 supporting datasetNkapd1em1(IMPC)MbpheterozygoteE9.5N/A * 
abnormal skin morphology2 supporting datasetsNkapd1em1(IMPC)MbpheterozygoteEarly adultN/A * 
increased freezing behavior1 supporting datasetNkapd1em1(IMPC)MbpheterozygoteEarly adult7.16x10-9 
abnormal visceral yolk sac morphology1 supporting datasetNkapd1em1(IMPC)MbpheterozygoteE9.5N/A * 
small kidney1 supporting datasetNkapd1em1(IMPC)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nkapd1em1(IMPC)MbpExon Deletionmouse
Nkapd1tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
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