Ncapd3 | non-SMC condensin II complex, subunit D3

GeneMGI:2142989Synonyms: 4632407J06Rik, B130055D15Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating HDL cholesterol level1 supporting datasetNcapd3em1(IMPC)JheterozygoteEarly adult3.13x10-5 
increased circulating aspartate transaminase level1 supporting datasetNcapd3em1(IMPC)JheterozygoteEarly adult4.24x10-7 
increased circulating phosphate level1 supporting datasetNcapd3em1(IMPC)JheterozygoteEarly adult5.72x10-7 
preweaning lethality, complete penetrance1 supporting datasetNcapd3em1(IMPC)JhomozygoteEarly adultN/A * 
increased circulating cholesterol level1 supporting datasetNcapd3em1(IMPC)JheterozygoteEarly adult6.42x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ncapd3em1(IMPC)JExon Deletionmouse
Ncapd3em1(IMPC)WtsiDeletionmouse
Ncapd3tm354108(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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