Myzap | myocardial zonula adherens protein

GeneMGI:2142908Synonyms: Myozap, Gcom1, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Skeleton Craniofacial

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

absent teeth1 supporting datasetMyzapem1(IMPC)JhomozygoteEarly adult5.61x10-6 
decreased circulating serum albumin level1 supporting datasetMyzapem1(IMPC)JhomozygoteEarly adult3.36x10-6 
decreased circulating HDL cholesterol level1 supporting datasetMyzapem1(IMPC)JhomozygoteEarly adult4.71x10-7 
decreased circulating total protein level1 supporting datasetMyzapem1(IMPC)JhomozygoteEarly adult1.69x10-5 
decreased circulating cholesterol level1 supporting datasetMyzapem1(IMPC)JhomozygoteEarly adult1.2x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Myzapem1(IMPC)JExon Deletionmouse
Myzaptm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Myzaptm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Myzaptm214938(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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