Hirip3 | HIRA interacting protein 3

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Growth/size/body region Hearing/vestibular/ear Nervous system Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	5 supporting datasets	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	3.31x10^-9
abnormal auditory brainstem response	1 supporting dataset	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	5.16x10^-5
increased heart weight	2 supporting datasets	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	2.77x10^-7
increased basophil cell number	1 supporting dataset	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	2.17x10^-6
abnormal behavior	1 supporting dataset	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.01x10^-6
abnormal uterus morphology	1 supporting dataset	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
decreased thigmotaxis	2 supporting datasets	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.01x10^-6
increased brain weight	1 supporting dataset	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.81x10^-8
increased neutrophil cell number	1 supporting dataset	Hirip3^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.34x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hirip3.

Associated images

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Histopathology

There is no histopathology data found for Hirip3.

IMPC related publications

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External links

No external links available for Hirip3.

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*Hirip3^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Hirip3^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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