Spred3 | sprouty-related EVH1 domain containing 3
Physiological systems
19 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Behavior/neurological Renal/urinary system
10 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged lymph nodes | 1 supporting dataset | Spred3em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Spred3em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Spred3em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| decreased prepulse inhibition | 1 supporting dataset | Spred3em1(IMPC)Tcp | heterozygote | Early adult | 6.92x10-6 | ||
| increased freezing behavior | 1 supporting dataset | Spred3em1(IMPC)Tcp | homozygote | Early adult | 9.43x10-5 | ||
| increased circulating creatinine level | 1 supporting dataset | Spred3em1(IMPC)Tcp | heterozygote | Early adult | 3.84x10-5 | ||
| enlarged ovary | 1 supporting dataset | Spred3em1(IMPC)Tcp | heterozygote | Early adult | N/A * |
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External links
No external links available for Spred3.
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| Spred3em1(IMPC)Tcp | Exon Deletion | | mouse |
| Spred3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Spred3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |