Nars2 | asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)

GeneMGI:2142075

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased thigmotaxis	4 supporting datasets	Nars2^em1(IMPC)J	heterozygote	Early adult	1.07x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Nars2^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Nars2^em1(IMPC)J	heterozygote	Early adult	8x10^-5
decreased exploration in new environment	1 supporting dataset	Nars2^em1(IMPC)J	heterozygote	Early adult	4.86x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Nars2^em1(IMPC)J	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nars2.

Associated images

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Histopathology

There is no histopathology data found for Nars2.

IMPC related publications

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External links

No external links available for Nars2.

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*Nars2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Nars2^{tm42847(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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