Alg8 | ALG8 alpha-1,3-glucosyltransferase

GeneMGI:2141959Synonyms: LOC381903

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Adipose tissue Embryo Growth/size/body region Behavior/neurological Skeleton Mortality/aging

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Alg8^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased bone mineral content	2 supporting datasets	Alg8^em1(IMPC)J	heterozygote	Early adult	3.61x10^-6
abnormal embryo size	1 supporting dataset	Alg8^em1(IMPC)J	homozygote	E9.5	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Alg8^em1(IMPC)J	heterozygote	Late adult	2.82x10^-8
abnormal vibrissa morphology	1 supporting dataset	Alg8^em1(IMPC)J	heterozygote	Early adult	9.34x10^-6
abnormal embryo turning	1 supporting dataset	Alg8^em1(IMPC)J	homozygote	E9.5	N/A ^*
decreased lean body mass	2 supporting datasets	Alg8^em1(IMPC)J	heterozygote	Early adult	4.76x10^-6
abnormal chorioallantoic fusion	1 supporting dataset	Alg8^em1(IMPC)J	homozygote	E9.5	N/A ^*
increased total body fat amount	2 supporting datasets	Alg8^em1(IMPC)J	heterozygote	Early adult	3.29x10^-5
embryonic growth retardation	1 supporting dataset	Alg8^em1(IMPC)J	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Alg8.

Associated images

Loading...

Histopathology

There is no histopathology data found for Alg8.

IMPC related publications

Loading...

External links

No external links available for Alg8.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Alg8^em1(IMPC)J*	Exon Deletion	‌	mouse
*Alg8^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes