Depdc5 | DEP domain containing 5

GeneMGI:2141101

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

5Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Depdc5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.76x10^-15
preweaning lethality, complete penetrance	1 supporting dataset	Depdc5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased total body fat amount	1 supporting dataset	Depdc5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.11x10^-5
impaired glucose tolerance	1 supporting dataset	Depdc5^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.88x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Depdc5.

Associated images

Loading...

Histopathology

There is no histopathology data found for Depdc5.

IMPC related publications

Loading...

External links

No external links available for Depdc5.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Depdc5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Depdc5^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Depdc5^{tm1c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse
*Depdc5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes